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Biodegradable Implants for Long-term Antibody Drug Delivery (2022-050)
Monoclonal antibodies have become increasingly valuable for treatment of a variety of diseases, such as age-related macular degeneration, various cancers, and inflammatory diseases. While these drugs have proven effective, they have a short half-life, and thus require repeated injections on a biweekly, monthly, or bimonthly basis which places a significant...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Thomas (TJ) Waterkotte, Yoonjee Park
Keywords(s):
Category(s): Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences, Technology Classifications > Advanced Materials, Technology Classifications > Life Sciences > Therapeutics
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High-Stability Nanopore-Based Resistive Pulse Sensing Design (2021-138)
Nanopore-based resistive pulse sensing techniques are widely used to detect biomolecules such as DNA and miRNA, as well as to sequence DNA. These techniques have many advantages, including high sensitivity, molecular selectivity, and a high signal-to-noise ratio.
Resistive pulse sensing with a biological nanopore requires a stable lipid membrane. Methods...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Essraa Khalil, Ryan White
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Sensors > Health-related Sensors, Technology Classifications > Life Sciences, Technology Classifications > Advanced Materials, Technology Classifications > Sensors
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Face Mask with Thermal Pathogen Inactivation (2020-008)
Face masks are a vital piece of personal protective equipment for healthcare workers, separating them from infectious pathogens. Despite their protective nature, pathogens can build up and survive on their surface. After a short amount of time, masks with built-up pathogens can infect the healthcare workers wearing them.
Dr. Shanov and his team have...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Soryong Chae, Hyunsik Kim, Yoontaek Oh, Yanbo Fang, Hung Nguyen, Vesselin Shanov
Keywords(s): COVID-19, Face Mask, Pathogen Inactivation
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > COVID-19, Technology Classifications > Life Sciences > Medical Devices, Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Advanced Materials, Technology Classifications > Advanced Materials > Healthcare-related materials > PPE
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Advanced Firefighter Apparel Material and Manufacturing Process (117-086)
Firefighters face great risks from heat and toxic chemicals in the line of duty, which can lead to heat-related death and cancer. Traditional protective apparel garments are thermally insulating but fail to dissipate heat quickly. Traditional garments also struggle to completely protect firefighters from toxic gases released in a fire.
Carbon nanotubes...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): David Mast, Richard Kleismit, Devika Chauhan, Ryan Noga, Vesselin Shanov, Chenhao Xu, Guangfeng Hou, Vianessa Ng, Zhangzhang Yin, Mark Schulz
Keywords(s):
Category(s): Technology Classifications > Advanced Materials, Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Advanced Materials > Healthcare-related materials > PPE
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High Purity Magnesium Single Crystal Production (115-008)
Magnesium (Mg) and magnesium-based alloys have favorable properties as biomedical materials due to their biocompatibility, mechanical properties and resorption in the body. However, Mg by itself suffers from a high corrosion rate, traditionally managed by alloying it with other elements, which may be toxic.
Recently, researchers at the University of...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Vesselin Shanov
Keywords(s): Biomedical materials, crystal growth, Directional solidification, High purity, Magnesium crystals, Magnesium single crystal, single crystal
Category(s): Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Life Sciences > Medical Devices, Technology Classifications > Advanced Materials, Technology Classifications > Life Sciences
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A Family of Therapeutic Delivery Systems (103-020)
The present invention is in the fields of molecular biology, biochemistry and pharmaceuticals. In general, the invention provides compositions for the cellular delivery of nucleic acids, polypeptides and/or molecular complexes comprising nucleic acids and polypeptides, and methods of making and using such compositions. The present invention provides...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Yemin Liu, Theresa Reineke
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Advanced Materials, Technology Classifications > Life Sciences
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