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Therapy for Addiction
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UC researchers have developed a monoclonal antibody that recognizes and effectively binds cocaine. By administering this antibody, cocaine concentrations are much lower in the brain, which aid individuals battling drug...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Nils Lonberg, Denise Williams, W. James Ball, Andrew Norman
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences > Diseases & Disorders > Neurologic, Technology Classifications > Life Sciences
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Biodegradable Implants for Long-term Antibody Drug Delivery (2022-050)
Monoclonal antibodies have become increasingly valuable for treatment of a variety of diseases, such as age-related macular degeneration, various cancers, and inflammatory diseases. While these drugs have proven effective, they have a short half-life, and thus require repeated injections on a biweekly, monthly, or bimonthly basis which places a significant...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Thomas (TJ) Waterkotte, Yoonjee Park
Keywords(s):
Category(s): Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences, Technology Classifications > Advanced Materials, Technology Classifications > Life Sciences > Therapeutics
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Potential Type 1 diabetes therapy (113-077)
Investigators at the University of Cincinnati have found a therapy that reverses new onset Type 1 diabetes in mouse models and may advance efforts in combating the disease among humans.
Type 1 diabetes (T1D) is an autoimmune disease affecting millions of people world-wide, and is currently incurable. Moreover, since the mid-20th century, the incidence...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): William Ridgway
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences > Diseases & Disorders > Diabetes-related, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics
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New Therapeutic Leads for Cachexia and Anorexia (112-005)
Dr. Glenn Millhauser and his lab at the University of California, Santa Cruz (UCSC) in collaboration with Dr. Stephen Benoit at the University of Cincinnati have discovered a group of proteins that will ultimately be of value in treating extreme cases of eating disorders such as anorexia or cachexia.
The agouti-related protein (AgRP) is produced in...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Stephen Benoit
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences > Diseases & Disorders > Digestive, Technology Classifications > Life Sciences > Diseases & Disorders > Neurologic, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics
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Novel Therapy for Type I Diabetes (110-077)
Dr. William Ridgway has found a potential new therapy for Type I diabetes.
T regulatory cells are very powerful down modulators of immune responses. We for the first time have shown that CD137pos cells are functionally and phenotypically different than normal Tregs and are more suppressive of immune function. In addition, we have now shown that CD137pos...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): William Ridgway
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Diabetes-related, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics
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