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Small Molecule Prolactin Receptor Inhibitors for Treatment of Cancers and Pain Disorders (117-018)
Each year, over a million women worldwide are diagnosed with breast cancer, accounting for 25% of all female cancers. About 1 in 8 women are predicted to develop this disease during her lifetime. Over the last two decades, single and combination chemotherapy, based on results from clinical trials, has led to a considerable reduction in morbidity and...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Armen Akopian, Abraham Domb, Edward Merino, Eric Hugo, Nira Ben-Jonathan
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Diseases & Disorders > Neurologic, Technology Classifications > Life Sciences > Therapeutics > Small Molecule, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics
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Hydrogen Peroxide-Activated Compounds as Selective Anti-Cancer Therapeutics (115026)
The design of DNA-based agents for cancer treatment has slowed dramatically because of the perception that these agents will have high levels of off-target effects on healthy, non-cancerous cells. Normal off-target effects include modification or interaction of DNA in these non-cancerous, highly replicating cells. This off-target reactivity limits tolerated...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Mark Wunderlich, James Mulloy, Safnas AbdulSalam, Anish Vadukoot, Edward Merino
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Biomedical
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Methods and Compounds for Treating Cancers (112070)
Dr. Edward Merino has created a novel strategy for the treatment of leukemia and renal cancers by using highly selective compounds. The compounds selectively trigger toxic reactions in cancer cells with increased reactive oxygen species. Reactive oxygen has been found to be at greater concentrations within these cancers. Due to strategic activation,...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): James Mulloy, Guori Li, Edward Merino
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics
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