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RU360 (106-087)
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM). Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ~10 M of Ru360 for 30 min). Does not affect other cellular Ca2+...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Mohammed Matlib
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Research Tools, Technology Classifications > Life Sciences
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