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Mouse Strain B6.FVB-Tg(GNAT2-Dta)98Wwk/J (108-112)
Mice hemizygous for this "Trc-Tox176" transgene (also called "h-GNAT2pro-DTA") are viable and fertile. Expression of diphtheria toxin (DTA) from the transgene is similar to that of endogenous GNAT2, leading to ablation of both rod and cone photoreceptor development in the ventral retina (the abnormality is a result of abnormal cellular...
Published: 8/30/2023   |   Updated: 8/30/2023   |   Inventor(s): Shao-Ling Fong, Sai-Xia Ying, Winston Kao
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Category(s): Technology Classifications > Life Sciences > Research Tools, Technology Classifications > Life Sciences