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Inhibition of Airway Hyperresponsivenes by Interleukin 31 Receptor Alpha in Asthma (2023-038)
Asthma is a chronic inflammatory airway characterized by airway hyperresponsiveness (AHR), airway inflammation, and goblet cell hyperplasia. AHR or the excessive response of the airways to a variety of stimuli is one of the cardinal features of asthma. AHR is a major cause of hospitalization, morbidity, and morality in allergic asthma; however, the...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Satish Madala, Santoshi Akkenapally
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diseases & Disorders > Respiratory
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Bio-Field Programmable Gate Array for PCR Detection (2022-106)
Coronavirus disease is an infectious disease caused by the SARS-CoV-2 virus. Covid-19 testing plays a critical role in the fight against the virus. Diagnostic tests can show if you currently are infected with SARS-CoV-2, the virus that causes Covid-19. However, PCR (polymerase chain reaction) testing is considered the “gold standard” in...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Chen-Yi Lee, Jiajie Diao
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > COVID-19, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders
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Three-Dimensional Echo Decorrelation Imaging for Thermal Ablation of Liver Cancer (2022-008)
Liver cancer is common in the United States, with over 36,000 Americans receiving a diagnosis of liver cancer each year. Thermal ablation, including radiofrequency and microwave ablation (RFA and MWA) is a useful treatment for liver cancer, but patient outcomes are inferior to that of surgery. Monitoring and controlling thermal ablation would overcome...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Peter Grimm, Elmira Ghahramani Z., T Mast
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Medical Devices
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High-Stability Nanopore-Based Resistive Pulse Sensing Design (2021-138)
Nanopore-based resistive pulse sensing techniques are widely used to detect biomolecules such as DNA and miRNA, as well as to sequence DNA. These techniques have many advantages, including high sensitivity, molecular selectivity, and a high signal-to-noise ratio.
Resistive pulse sensing with a biological nanopore requires a stable lipid membrane. Methods...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Essraa Khalil, Ryan White
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Sensors > Health-related Sensors, Technology Classifications > Life Sciences, Technology Classifications > Advanced Materials, Technology Classifications > Sensors
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Non-Invasive Hydrogen Monitoring Device to Assess Gut Health (2021-114)
Humans do not produce hydrogen gas; however, many microbes found in the human gut do. The hydrogen produced from gut microbiota can have beneficial effects, but an excess of hydrogen can also have harmful effects on the human host, as it is proposed to be associated with various gastrointestinal disorders.
Hydrogen gas produced by the microbes in the...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Senu Apewokin, Michael Smith, Peng Zhang, Racheal Wilkinson, Sarah Pixley Bell, William Heineman
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Digestive, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diagnostics
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Syringe Based Rapid Processor for Small Biopsies (2019-050)
There is a significant unmet need in the field of pathology for rapid processing of small biopsies which allows clinicians to make a preliminary diagnosis prior to patient discharge. The current methodology to process “immediate reads” involves running a standard tissue processor coupled with traditional embedding technique, which are both...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Paul Lee
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences
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Single Molecule Epigenetic Localization (2019-047)
DNA epigenetic modifications play important functions in a broad range of physiological and pathological processes and their dysregulation can lead to various human diseases. 5-hydroxymethylcytosine (5hmC) is one of the major mammalian DNA epigenetic modifications and is believed to be a gene activation marker in development and disease. Recently, 5hmC...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Chunxiao Song, Jiajie Diao
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Other Life Sciences
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Plasma Test to Assess Liver Disease Severity (2019-018)
The number of people diagnosed with liver disease was 4.9 million in 2016 with 40,326 dying from this disease in the US. Liver disease can be either inherited or caused by a variety of factors that can cause damage to the liver such as viruses, alcohol use, and obesity. In the early stage of any liver disease, liver may become inflamed. However, an...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Patrick Van Dreden, Clayton Lewis, Vladimir Bogdanov
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Diseases & Disorders > Digestive, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders
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A Prognostic Test for Early-Stage Breast Lesions
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Dr. Georg F. Weber, Professor in the College of Pharmacy has developed a test to determine the risk for pre-malignant lesions to turn into breast cancer. This novel assessment utilizes variants of the progression mediator osteopontin...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Georg Weber
Keywords(s): Biological Assessment, Diagnostic Testing, Early-Stage Breast Lesions, Healthcare, Osteopontin Variants
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences
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Nanopipette Device for Label-Free, Rapid Liquid Cancer Biopsy (117-042)
Early cancer detection is crucial for survival. Many cancer screening methods and biopsies, though, require complex and invasive surgical procedures causing cancers to go undetected during the early stages. Exosomes, or cell-secreted nanoscale extracellular vesicles, contain biomarkers that indicate cancers and other diseases, and they are constantly...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Leyla Esfandiari
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Research Tools, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Medical Devices, Technology Classifications > Life Sciences
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