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Therapy for Addiction
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UC researchers have developed a monoclonal antibody that recognizes and effectively binds cocaine. By administering this antibody, cocaine concentrations are much lower in the brain, which aid individuals battling drug...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Nils Lonberg, Denise Williams, W. James Ball, Andrew Norman
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences > Diseases & Disorders > Neurologic, Technology Classifications > Life Sciences
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Compounds to Treat Obesity (104-010)
Obesity is now considered as a global epidemic with over one billion people being overweight. About $33 billion is being spent each year in USA on weight reduction products. To date no satisfactory drug is available to control obesity. Therefore, millions of dollars are spent each year towards the development of new treatments to fight this epidemic.
Neuropeptide...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Ambikaipakan Balasubramanium
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics > Biomaterials, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diseases & Disorders > Cardiovascular, Technology Classifications > Life Sciences > Diseases & Disorders > Diabetes-related
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Immunotherapeutic Phospholipid for Cancer Treatment (2023-012)
A hallmark feature of malignant cell growth is the presence of an immunosuppressive tumor microenvironment (TME). Cancer cells have evolved mechanisms that promote the escape from the host immune attack which sustains tumor growth. Reversal of immunosuppression in the TME is now considered a powerful approach for cancer treatment.
The TME is a complex...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Xiaoyang Qi
Keywords(s): Cancer, Healthcare, Immune System, Immunotherapeutic Phospholipid, Tumor Microenvironment (TME)
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diseases & Disorders > Autoimmune, Technology Classifications > Life Sciences > Therapeutics > Biomaterials, Technology Classifications > Life Sciences > Therapeutics
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Drug Delivery Device For Treatment of Brain Tumors (2022-069)
Glioblastoma (GBM) is the most common and aggressive form of brain cancer in adults. Due to the rapid growth rate and infiltrative nature of the tumor, currently available therapies for treating GBM have increased median survival to only around fifteen months.
GBM resistance to therapies leads to poor outcomes in patients with GBM and eventually patient...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Betty Tyler, Henry Brem, Safwan Alomari, Daewoo Han, Andrew Steckl
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics
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Biodegradable Implants for Long-term Antibody Drug Delivery (2022-050)
Monoclonal antibodies have become increasingly valuable for treatment of a variety of diseases, such as age-related macular degeneration, various cancers, and inflammatory diseases. While these drugs have proven effective, they have a short half-life, and thus require repeated injections on a biweekly, monthly, or bimonthly basis which places a significant...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Thomas (TJ) Waterkotte, Yoonjee Park
Keywords(s):
Category(s): Technology Classifications > Advanced Materials > Healthcare-related materials, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences, Technology Classifications > Advanced Materials, Technology Classifications > Life Sciences > Therapeutics
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Patient-specific biodegradable drug delivery (2022-035)
Biomaterial implants fabricated from synthetic polymers have been extensively used in regenerative medicine applications and are regularly formulated into erodible drug delivery systems or degradable scaffolds. These implants are most commonly degraded by hydrolysis. While these materials can be effective, their degradation rates are pre-determined;...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Karina Bruce, Dylan Marques, Alan Fullenkamp, John Martin
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics > Biomaterials, Technology Classifications > Life Sciences > Regenerative Medicine, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics
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Investigation of Supramolecular Interactions of Polyphenolic Host with an Anti-Fibrotic Drug (2021-148)
Acne vulgaris is a complex skin disorder involving multiple abnormalities of the pilosebaceous unit. Acne is doubtless the most frequent skin disease worldwide during puberty and worsens throughout adolescence. Although acne has a tendency of self-healing, scars caused by acne without a timely treatment may severely affect the life quality on the patient...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Suchitra Panigrahi, Harshita Kumari
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Skin, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders
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Potent Therapeutics for Hyponatremia and Polycystic Kidney Disease (2021-097)
Hyponatremia is a frequent and common electrolyte abnormality, characterized by a decrease in sodium concentration in the blood. Dilutional hyponatremia results from water imbalance associated with abnormal elevation in circulating levels of vasopressin. Polycystic kidney disease (PKD) is another condition that is highly linked to the activity of vasopressin...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Hassane Amlal
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences
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Lipocalin 10 as a Therapeutic Agent for Inflammation-Induced Organ Dysfunction (2021-070)
Despite recent advances in antibiotic therapy and supportive critical care, sepsis remains a leading cause of death in intensive care units. Currently, the increased vascular permeability is well-recognized to be responsible for inflammation-/sepsis-triggered organ failure and patient mortality.
There is positive connection between vascular leakage,...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Xiaohong Wang, Yutian Li, Guo-Chang Fan
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Other Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences
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Novel Calibration Phantom for Improved Proton Radiotherapy Outcomes (2020-143)
Proton radiotherapy involves precise delivery of high doses of radiation to treat cancer. Protons travel a certain distance into the tissue, and energy is released only at the target site. This makes proton radiotherapy more precise than traditional radiation treatment, and less destructive to surrounding healthy tissue. However, full optimization of...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Peter Sandwall, Michael Lamba, Samuel Glover, Henry Spitz, Jimmy Stringer
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Biomedical, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Medical Devices
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