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Novel Method for Pleurodesis and Delivery of Drugs to Lung and Pleural Space
Pleurodesis is a method used to treat pathological collection of air or liquid in the chest cavity, termed pneumothorax (collapsed lung) or pleural effusion (which can be malignant or benign), respectively, which pose daily management challenges in virtually every major hospital. Pleurodesis is accomplished by interventions that induce fusion of the...
Published: 9/14/2023
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Updated: 9/14/2023
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Inventor(s): Francis McCormack, Yusuke Tanaka
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Respiratory, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences
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Novel Treatment Strategies for Pancreatic Cancer using Recombinant Acid Sphingomyelinase (2023-072)
Pancreatic Adenocarcinoma (PDAC) is one of the most common cancers worldwide. Despite decade of advancement and research into the multimodal care of PDAC, the outlook remains grim. The majority of patients with PDAC present with metastatic disease at time of diagnosis. Only a minority of patients present with potentially respectable disease and even...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Gregory Wilson, Erich Gulbins, Syed Ahmad
Keywords(s): Acid Sphingomyelinase, Cancer, Healthcare, Pancreatic Adenocarcinoma (PDAC), Tumor Progression
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Diseases & Disorders
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Inhibition of Airway Hyperresponsivenes by Interleukin 31 Receptor Alpha in Asthma (2023-038)
Asthma is a chronic inflammatory airway characterized by airway hyperresponsiveness (AHR), airway inflammation, and goblet cell hyperplasia. AHR or the excessive response of the airways to a variety of stimuli is one of the cardinal features of asthma. AHR is a major cause of hospitalization, morbidity, and morality in allergic asthma; however, the...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Satish Madala, Santoshi Akkenapally
Keywords(s):
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diseases & Disorders > Respiratory
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Therapy for Addiction
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UC researchers have developed a monoclonal antibody that recognizes and effectively binds cocaine. By administering this antibody, cocaine concentrations are much lower in the brain, which aid individuals battling drug...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Nils Lonberg, Denise Williams, W. James Ball, Andrew Norman
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Therapeutics > Protein Therapies, Technology Classifications > Life Sciences > Diseases & Disorders > Neurologic, Technology Classifications > Life Sciences
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Compounds to Treat Obesity (104-010)
Obesity is now considered as a global epidemic with over one billion people being overweight. About $33 billion is being spent each year in USA on weight reduction products. To date no satisfactory drug is available to control obesity. Therefore, millions of dollars are spent each year towards the development of new treatments to fight this epidemic.
Neuropeptide...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Ambikaipakan Balasubramanium
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Therapeutics > Biomaterials, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diseases & Disorders > Cardiovascular, Technology Classifications > Life Sciences > Diseases & Disorders > Diabetes-related
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Immunotherapeutic Phospholipid for Cancer Treatment (2023-012)
A hallmark feature of malignant cell growth is the presence of an immunosuppressive tumor microenvironment (TME). Cancer cells have evolved mechanisms that promote the escape from the host immune attack which sustains tumor growth. Reversal of immunosuppression in the TME is now considered a powerful approach for cancer treatment.
The TME is a complex...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Xiaoyang Qi
Keywords(s): Cancer, Healthcare, Immune System, Immunotherapeutic Phospholipid, Tumor Microenvironment (TME)
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences > Diseases & Disorders > Autoimmune, Technology Classifications > Life Sciences > Therapeutics > Biomaterials, Technology Classifications > Life Sciences > Therapeutics
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Bio-Field Programmable Gate Array for PCR Detection (2022-106)
Coronavirus disease is an infectious disease caused by the SARS-CoV-2 virus. Covid-19 testing plays a critical role in the fight against the virus. Diagnostic tests can show if you currently are infected with SARS-CoV-2, the virus that causes Covid-19. However, PCR (polymerase chain reaction) testing is considered the “gold standard” in...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Chen-Yi Lee, Jiajie Diao
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > COVID-19, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders
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Drug Delivery Device For Treatment of Brain Tumors (2022-069)
Glioblastoma (GBM) is the most common and aggressive form of brain cancer in adults. Due to the rapid growth rate and infiltrative nature of the tumor, currently available therapies for treating GBM have increased median survival to only around fifteen months.
GBM resistance to therapies leads to poor outcomes in patients with GBM and eventually patient...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Betty Tyler, Henry Brem, Safwan Alomari, Daewoo Han, Andrew Steckl
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics
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Three-Dimensional Echo Decorrelation Imaging for Thermal Ablation of Liver Cancer (2022-008)
Liver cancer is common in the United States, with over 36,000 Americans receiving a diagnosis of liver cancer each year. Thermal ablation, including radiofrequency and microwave ablation (RFA and MWA) is a useful treatment for liver cancer, but patient outcomes are inferior to that of surgery. Monitoring and controlling thermal ablation would overcome...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Peter Grimm, Elmira Ghahramani Z., T Mast
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Cancer, Technology Classifications > Life Sciences > Diseases & Disorders, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Medical Devices
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Investigation of Supramolecular Interactions of Polyphenolic Host with an Anti-Fibrotic Drug (2021-148)
Acne vulgaris is a complex skin disorder involving multiple abnormalities of the pilosebaceous unit. Acne is doubtless the most frequent skin disease worldwide during puberty and worsens throughout adolescence. Although acne has a tendency of self-healing, scars caused by acne without a timely treatment may severely affect the life quality on the patient...
Published: 8/30/2023
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Updated: 8/30/2023
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Inventor(s): Suchitra Panigrahi, Harshita Kumari
Keywords(s):
Category(s): Technology Classifications > Life Sciences > Diseases & Disorders > Skin, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Diseases & Disorders
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